# Combined IV and Topical TXA in Major Spine Surgery

> **NCT04797156** · EARLY_PHASE1 · COMPLETED · sponsor: **Icahn School of Medicine at Mount Sinai** · enrollment: 65 (actual)

## Conditions studied

- Spine Surgery
- Back Pain

## Interventions

- **DRUG:** High Dose Tranexamic acid
- **DRUG:** Low Dose Tranexamic acid
- **DRUG:** Tranexamic acid Topical
- **DRUG:** Normal saline

## Key facts

- **NCT ID:** NCT04797156
- **Lead sponsor:** Icahn School of Medicine at Mount Sinai
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-03-03
- **Primary completion:** 2024-08-15
- **Final completion:** 2024-08-15
- **Target enrollment:** 65 (ACTUAL)
- **Last updated:** 2025-04-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04797156

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04797156, "Combined IV and Topical TXA in Major Spine Surgery". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT04797156. Licensed CC0.

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