# THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy

> **NCT04815694** · NA · UNKNOWN · sponsor: **Fondazione Policlinico Universitario Agostino Gemelli IRCCS** · enrollment: 63 (estimated)

## Conditions studied

- Neoadjuvant Chemoradiotherapy
- Locally Advanced Rectal Cancer
- Pathological Complete Response

## Interventions

- **RADIATION:** RT Dose escalation in LARC patients with an Early Regression Index > 13.1 at second week on nCRT

## Key facts

- **NCT ID:** NCT04815694
- **Lead sponsor:** Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2021-03-17
- **Primary completion:** 2022-03-30
- **Final completion:** 2022-09-30
- **Target enrollment:** 63 (ESTIMATED)
- **Last updated:** 2021-03-25

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04815694

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04815694, "THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04815694. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
