# Study Evaluating the Effect of Food on the Pharmacokinetics of Palovarotene and the Effect of Palovarotene on the Pharmacokinetics of the CYP3A4 Substrate Midazolam in Two Cohorts of Healthy Adult Subjects

> **NCT04829773** · PHASE1 · COMPLETED · sponsor: **Clementia Pharmaceuticals Inc.** · enrollment: 48 (actual)

## Conditions studied

- Fibrodysplasia Ossificans Progressiva

## Interventions

- **DRUG:** Palovarotene
- **DRUG:** midazolam

## Key facts

- **NCT ID:** NCT04829773
- **Lead sponsor:** Clementia Pharmaceuticals Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-01-03
- **Primary completion:** 2019-03-29
- **Final completion:** 2019-03-29
- **Target enrollment:** 48 (ACTUAL)
- **Last updated:** 2021-04-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04829773

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04829773, "Study Evaluating the Effect of Food on the Pharmacokinetics of Palovarotene and the Effect of Palovarotene on the Pharmacokinetics of the CYP3A4 Substrate Midazolam in Two Cohorts of Healthy Adult Subjects". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT04829773. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*