# A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder

> **NCT04832425** · PHASE2,PHASE3 · COMPLETED · sponsor: **Praxis Precision Medicines** · enrollment: 216 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** PRAX-114
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04832425
- **Lead sponsor:** Praxis Precision Medicines
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-03-30
- **Primary completion:** 2022-05-05
- **Final completion:** 2022-05-05
- **Target enrollment:** 216 (ACTUAL)
- **Last updated:** 2022-07-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04832425

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04832425, "A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04832425. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*