# Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

> **NCT04847063** · PHASE1 · RECRUITING · sponsor: **National Cancer Institute (NCI)** · enrollment: 60 (estimated)

## Conditions studied

- Peritoneal Mesothelioma
- Peritoneal Carcinomatosis
- Ovarian Cancer
- Gastrointestinal Cancer
- Appendiceal Cancer
- Atypical Mesothelial Proliferation
- Colorectal Cancer

## Interventions

- **DRUG:** Sodium Thiosulfate
- **DRUG:** 5-Fluorouracil
- **DRUG:** Oxaliplatin
- **DRUG:** Doxorubicin
- **PROCEDURE:** Hyperthermic Intraperitonial Chemotherapy
- **DRUG:** Cisplatin
- **DRUG:** Mitomycin C

## Key facts

- **NCT ID:** NCT04847063
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-10-19
- **Primary completion:** 2033-12-30
- **Final completion:** 2034-12-30
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2026-04-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04847063

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04847063, "Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04847063. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*