# Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder

> **NCT04847245** · NA · UNKNOWN · sponsor: **Peking University** · enrollment: 80 (estimated)

## Conditions studied

- Chronic Visceral Pain
- Major Depressive Disorder

## Interventions

- **DRUG:** Pregabalin 75mg tid + Duloxetine
- **DRUG:** Intravenous administration of esketamine 0.125 mg/kg+Duloxetine
- **DRUG:** Intravenous administration of esketamine 0.25 mg/kg +Duloxetine
- **DRUG:** Intravenous administration of esketamine 0.50 mg/kg+Duloxetine

## Key facts

- **NCT ID:** NCT04847245
- **Lead sponsor:** Peking University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2021-05-01
- **Primary completion:** 2022-12-31
- **Final completion:** 2023-03-01
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2021-04-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04847245

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04847245, "Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04847245. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*