# ONC201 and Radiation Therapy Before Surgery for the Treatment of Recurrent Glioblastoma

> **NCT04854044** · PHASE1 · WITHDRAWN · sponsor: **Jonsson Comprehensive Cancer Center**

## Conditions studied

- Recurrent Glioblastoma
- Recurrent Gliosarcoma
- Recurrent Supratentorial Glioblastoma
- Supratentorial Gliosarcoma

## Interventions

- **DRUG:** Akt/ERK Inhibitor ONC201
- **RADIATION:** Radiation Therapy
- **PROCEDURE:** Resection

## Key facts

- **NCT ID:** NCT04854044
- **Lead sponsor:** Jonsson Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2021-05-01
- **Primary completion:** 2025-07-01
- **Final completion:** 2026-07-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** The P.I. is not prepared to move forward at this thime
- **Last updated:** 2021-05-12

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04854044

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04854044, "ONC201 and Radiation Therapy Before Surgery for the Treatment of Recurrent Glioblastoma". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04854044. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
