# Premedication with Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty

> **NCT04859283** · PHASE4 · COMPLETED · sponsor: **Turku University Hospital** · enrollment: 100 (actual)

## Conditions studied

- Knee Osteoarthritis
- Pain, Postoperative

## Interventions

- **DRUG:** Dexmedetomidine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04859283
- **Lead sponsor:** Turku University Hospital
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-06-10
- **Primary completion:** 2023-09-15
- **Final completion:** 2025-01-20
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2025-01-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04859283

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04859283, "Premedication with Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty". Retrieved via AI Analytics 2026-07-07 from https://api.ai-analytics.org/clinical/NCT04859283. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*