# Effectiveness of Splinting After Collagenase Injection

> **NCT04874870** · PHASE3 · COMPLETED · sponsor: **Foundation for Orthopaedic Research and Education** · enrollment: 80 (actual)

## Conditions studied

- Dupuytren Contracture
- Dupuytren's Disease

## Interventions

- **DRUG:** Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex]
- **COMBINATION_PRODUCT:** Xiaflex + Hand-Based Custom Orthosis

## Key facts

- **NCT ID:** NCT04874870
- **Lead sponsor:** Foundation for Orthopaedic Research and Education
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-12
- **Primary completion:** 2023-12-01
- **Final completion:** 2023-12-01
- **Target enrollment:** 80 (ACTUAL)
- **Last updated:** 2025-02-26

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04874870

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04874870, "Effectiveness of Splinting After Collagenase Injection". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04874870. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*