# BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer

> **NCT04891068** · PHASE2 · RECRUITING · sponsor: **University of Illinois at Chicago** · enrollment: 40 (estimated)

## Conditions studied

- Breast Cancer Invasive
- Early-stage Breast Cancer
- High Risk Breast Carcinoma

## Interventions

- **DRUG:** Azacitidine

## Key facts

- **NCT ID:** NCT04891068
- **Lead sponsor:** University of Illinois at Chicago
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-01-10
- **Primary completion:** 2026-05
- **Final completion:** 2026-05
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2026-01-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04891068

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04891068, "BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer". Retrieved via AI Analytics 2026-07-05 from https://api.ai-analytics.org/clinical/NCT04891068. Licensed CC0.

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