# Measurement of NAD+ Synthesis in Human Skeletal Muscle

> **NCT04905446** · NA · COMPLETED · sponsor: **AdventHealth Translational Research Institute** · enrollment: 15 (actual)

## Conditions studied

- Skeletal Muscle

## Interventions

- **OTHER:** Deuterated nicotinamide (D4-NAM) IV infusion
- **PROCEDURE:** Skeletal muscle biopsy
- **PROCEDURE:** Skin tissue biopsy

## Key facts

- **NCT ID:** NCT04905446
- **Lead sponsor:** AdventHealth Translational Research Institute
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-09-10
- **Primary completion:** 2022-06-14
- **Final completion:** 2024-12-20
- **Target enrollment:** 15 (ACTUAL)
- **Last updated:** 2025-03-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04905446

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04905446, "Measurement of NAD+ Synthesis in Human Skeletal Muscle". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT04905446. Licensed CC0.

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