# The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance

> **NCT04908358** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Massachusetts General Hospital** · enrollment: 126 (actual)

## Conditions studied

- Aging

## Interventions

- **OTHER:** Active transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions
- **OTHER:** Sham transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions

## Key facts

- **NCT ID:** NCT04908358
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2021-11-24
- **Primary completion:** 2026-08-31
- **Final completion:** 2026-08-31
- **Target enrollment:** 126 (ACTUAL)
- **Last updated:** 2026-03-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04908358

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04908358, "The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04908358. Licensed CC0.

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