# Are Standard Dosing Regimens of Piperacillin-Tazobactam Suitable in Critically Ill Patients With Open Abdomen and Negative Pressure Wound Therapy? A Population Pharmacokinetic Study.

> **NCT04915872** · — · COMPLETED · sponsor: **University Hospital, Bordeaux** · enrollment: 46 (actual)

## Conditions studied

- Laparotomy
- Critical Illness
- Piperacillin, Tazobactam Drug Combination

## Interventions

- **PROCEDURE:** Blood sampling (T0, inclusion)
- **PROCEDURE:** other samplings (T1)

## Key facts

- **NCT ID:** NCT04915872
- **Lead sponsor:** University Hospital, Bordeaux
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-01
- **Primary completion:** 2022-11-18
- **Final completion:** 2023-01-27
- **Target enrollment:** 46 (ACTUAL)
- **Last updated:** 2023-02-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04915872

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04915872, "Are Standard Dosing Regimens of Piperacillin-Tazobactam Suitable in Critically Ill Patients With Open Abdomen and Negative Pressure Wound Therapy? A Population Pharmacokinetic Study.". Retrieved via AI Analytics 2026-06-13 from https://api.ai-analytics.org/clinical/NCT04915872. Licensed CC0.

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