# Protocolised Early De-Resuscitation in Septic Shock (REDUCE)

> **NCT04931485** · NA · COMPLETED · sponsor: **Insel Gruppe AG, University Hospital Bern** · enrollment: 170 (actual)

## Conditions studied

- Septic Shock

## Interventions

- **OTHER:** Fluid management according to the REDUCE Fluid Protocol
- **OTHER:** Standard of care

## Key facts

- **NCT ID:** NCT04931485
- **Lead sponsor:** Insel Gruppe AG, University Hospital Bern
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-19
- **Primary completion:** 2025-02-10
- **Final completion:** 2025-05-07
- **Target enrollment:** 170 (ACTUAL)
- **Last updated:** 2026-05-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04931485

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04931485, "Protocolised Early De-Resuscitation in Septic Shock (REDUCE)". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT04931485. Licensed CC0.

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