# Opioid-Free Anesthesia in Cardiac Surgery

> **NCT04940689** · PHASE3 · COMPLETED · sponsor: **University Hospital, Rouen** · enrollment: 268 (actual)

## Conditions studied

- Anesthesia

## Interventions

- **DRUG:** Dexmédétomidine 0.5 g/kg + lidocaine 1.5 mg/kg
- **DRUG:** Remifentanil

## Key facts

- **NCT ID:** NCT04940689
- **Lead sponsor:** University Hospital, Rouen
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-22
- **Primary completion:** 2024-08-28
- **Final completion:** 2024-08-28
- **Target enrollment:** 268 (ACTUAL)
- **Last updated:** 2026-03-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04940689

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04940689, "Opioid-Free Anesthesia in Cardiac Surgery". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04940689. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*