# Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies.

> **NCT04965649** · — · UNKNOWN · sponsor: **Centre Hospitalier Universitaire de Nīmes** · enrollment: 30 (estimated)

## Conditions studied

- Leukemia
- Myelogenous Leukemia
- Chronic Leukemia
- BCR-ABL Positive Acute Myeloid Leukemia

## Interventions

- **GENETIC:** Phenotyping of total and innate CD8+T cells by flow cytometry

## Key facts

- **NCT ID:** NCT04965649
- **Lead sponsor:** Centre Hospitalier Universitaire de Nīmes
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2021-01-01
- **Primary completion:** 2024-07-01
- **Final completion:** 2025-01-01
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2023-08-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04965649

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04965649, "Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies.". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT04965649. Licensed CC0.

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