# A Clinical Trial of Adjunctive and Monotherapy PRAX-114 in Participants With Major Depressive Disorder

> **NCT04969510** · PHASE2 · COMPLETED · sponsor: **Praxis Precision Medicines** · enrollment: 110 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** 10 mg PRAX-114
- **DRUG:** 20 mg PRAX-114
- **DRUG:** 40 mg PRAX-114
- **DRUG:** 60 mg PRAX-114
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04969510
- **Lead sponsor:** Praxis Precision Medicines
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-06-24
- **Primary completion:** 2022-07-15
- **Final completion:** 2022-08-02
- **Target enrollment:** 110 (ACTUAL)
- **Last updated:** 2022-08-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04969510

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04969510, "A Clinical Trial of Adjunctive and Monotherapy PRAX-114 in Participants With Major Depressive Disorder". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04969510. Licensed CC0.

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