# NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome

> **NCT04977388** · PHASE1,PHASE2 · COMPLETED · sponsor: **Stephen G. Kaler, MD** · enrollment: 3 (actual)

## Conditions studied

- Menkes Disease
- Occipital Horn Syndrome

## Interventions

- **DRUG:** Droxidopa
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT04977388
- **Lead sponsor:** Stephen G. Kaler, MD
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-12
- **Primary completion:** 2023-10-30
- **Final completion:** 2024-06-29
- **Target enrollment:** 3 (ACTUAL)
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04977388

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04977388, "NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT04977388. Licensed CC0.

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