# Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)

> **NCT04978324** · PHASE3 · WITHDRAWN · sponsor: **Virginia Commonwealth University**

## Conditions studied

- Periodontitis Chronic Generalized Severe
- Periodontitis Chronic Generalized Moderate

## Interventions

- **BIOLOGICAL:** leukocyte platelet rich fibrin (L-PRF)
- **PROCEDURE:** Scaling and Root Planing

## Key facts

- **NCT ID:** NCT04978324
- **Lead sponsor:** Virginia Commonwealth University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2022-05
- **Primary completion:** 2022-12
- **Final completion:** 2022-12
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Fellow graduated before successfully enrolling any participants
- **Last updated:** 2022-05-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04978324

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04978324, "Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04978324. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
