# A Study of Pevonedistat Combined With Decitabine and Cedazuridine in Adults With Higher-risk Myelodysplastic Syndromes

> **NCT04985656** · PHASE2 · WITHDRAWN · sponsor: **Takeda**

## Conditions studied

- Myelodysplastic Syndromes (MDS)

## Interventions

- **DRUG:** Pevonedistat
- **DRUG:** Decitabine
- **DRUG:** Cedazuridine

## Key facts

- **NCT ID:** NCT04985656
- **Lead sponsor:** Takeda
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2021-10-01
- **Primary completion:** 2024-01-08
- **Final completion:** 2024-11-08
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Sponsor Decision to Terminate Trial
- **Last updated:** 2021-09-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04985656

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04985656, "A Study of Pevonedistat Combined With Decitabine and Cedazuridine in Adults With Higher-risk Myelodysplastic Syndromes". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04985656. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*