# Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

> **NCT04985942** · PHASE3 · COMPLETED · sponsor: **Intra-Cellular Therapies, Inc.** · enrollment: 485 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** Lumateperone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04985942
- **Lead sponsor:** Intra-Cellular Therapies, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-07-30
- **Primary completion:** 2024-02-22
- **Final completion:** 2024-02-27
- **Target enrollment:** 485 (ACTUAL)
- **Last updated:** 2025-05-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04985942

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04985942, "Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04985942. Licensed CC0.

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