Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia

NCT04994808 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

23

Enrollment

OTHER

Sponsor class

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndrome

Interventions

DRUG: Clofarabine
DRUG: Fludarabine
PROCEDURE: Hematopoietic Cell Transplantation
RADIATION: Total-Body Irradiation
DRUG: Treosulfan
PROCEDURE: Echocardiography Test
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Lumbar Puncture
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Biospecimen Collection

Sponsor

Fred Hutchinson Cancer Center

Collaborators

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