# Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis

> **NCT04998188** · NA · RECRUITING · sponsor: **Istituto Ortopedico Rizzoli** · enrollment: 204 (estimated)

## Conditions studied

- Knee Osteoarthritis

## Interventions

- **PROCEDURE:** Collagen
- **PROCEDURE:** Placebo (saline solution)

## Key facts

- **NCT ID:** NCT04998188
- **Lead sponsor:** Istituto Ortopedico Rizzoli
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-02-16
- **Primary completion:** 2027-12
- **Final completion:** 2027-12
- **Target enrollment:** 204 (ESTIMATED)
- **Last updated:** 2026-02-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04998188

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04998188, "Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04998188. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*