# Fluoride Delivery to Prevent White Spots During Orthodontic Treatment

> **NCT05005689** · PHASE4 · UNKNOWN · sponsor: **Liverpool University Hospitals NHS Foundation Trust** · enrollment: 130 (estimated)

## Conditions studied

- Orthodontic Appliance Complication
- Tooth Demineralization

## Interventions

- **DRUG:** Fluoride mouthwash (0.05%; 225ppm).
- **DRUG:** Tooth Mousse Plus

## Key facts

- **NCT ID:** NCT05005689
- **Lead sponsor:** Liverpool University Hospitals NHS Foundation Trust
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2023-10-20
- **Primary completion:** 2025-09-30
- **Final completion:** 2025-09-30
- **Target enrollment:** 130 (ESTIMATED)
- **Last updated:** 2023-11-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05005689

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05005689, "Fluoride Delivery to Prevent White Spots During Orthodontic Treatment". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT05005689. Licensed CC0.

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