# Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia

> **NCT05008874** · — · TERMINATED · sponsor: **SwanBio Therapeutics, Inc.** · enrollment: 65 (actual)

## Conditions studied

- AMN
- AMN Gene Mutation
- X-ALD

## Interventions

- **OTHER:** Natural History Observation

## Key facts

- **NCT ID:** NCT05008874
- **Lead sponsor:** SwanBio Therapeutics, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** TERMINATED
- **Start date:** 2021-06-21
- **Primary completion:** 2025-05-16
- **Final completion:** 2025-05-16
- **Target enrollment:** 65 (ACTUAL)
- **Why stopped:** The AMN program requires significantly more time, patients, and resources, including the manufacture of additional investigational product, than what is currently available to Spur.
- **Last updated:** 2025-10-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05008874

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05008874, "Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05008874. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*