Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).

NCT05012098 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

11

Enrollment

NIH

Sponsor class

Conditions

Olfactory Neuroblastoma
Esthesioneuroblastoma
Neoplasm of the Nasal Cavity

Interventions

DRUG: Bintrafusp alfa/M7824
DRUG: Ibuprofen
DIAGNOSTIC_TEST: PET scan
DIAGNOSTIC_TEST: CT scan
PROCEDURE: Tumor tissue biopsy
DIAGNOSTIC_TEST: Brain MRI
DIAGNOSTIC_TEST: Dotate scan
DIAGNOSTIC_TEST: PET FDG scan
DIAGNOSTIC_TEST: Nuclear bone scan
DIAGNOSTIC_TEST: EKG

Sponsor

National Cancer Institute (NCI)