Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease

Conditions

• Parkinson Disease
• Gait Disorders, Neurologic
• Disease Progression
• Subthalamic Nucleus
• Accidental Fall
• Deep Brain Stimulation

Interventions

• DEVICE: High-Frequency-Only Stimulation
• DEVICE: Low-Frequency-Only Stimulation
• DEVICE: Alternating, 50 sec High-Frequency, 10 sec Low-Frequency Stimulation
• DEVICE: Alternating, 50 sec High-Frequency, 50 sec Low-Frequency Stimulation
• DEVICE: Alternating, 10 sec High-Frequency, 50 sec Low-Frequency Stimulation
• DEVICE: Alternating, 10 sec High-Frequency, 10 sec Low-Frequency Stimulation
• DRUG: OFF Dopaminergic Medication
• DRUG: ON Dopaminergic Medication

Sponsor

James Liao