# The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement

> **NCT05023278** · PHASE4 · COMPLETED · sponsor: **University of California, San Francisco** · enrollment: 100 (actual)

## Conditions studied

- Acute Pain
- Chronic Pain
- Knee Pain Chronic
- Neuropathic Pain

## Interventions

- **DRUG:** Venlafaxine 37.5 MG
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05023278
- **Lead sponsor:** University of California, San Francisco
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-05-10
- **Primary completion:** 2025-02-28
- **Final completion:** 2025-03-31
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2025-05-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05023278

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05023278, "The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05023278. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*