# Proof of Concept Trial of Adjuvant Activity of SWE, a Squalene-based -Oil-in-water Emulsion

> **NCT05035680** · PHASE1 · WITHDRAWN · sponsor: **Gates Medical Research Institute**

## Conditions studied

- Influenza

## Interventions

- **BIOLOGICAL:** Unadjuvanted seasonal influenza vaccine
- **BIOLOGICAL:** SWE adjuvant mixed with unadjuvanted seasonal influenza vaccine shortly before dosing (SWE + QIV)
- **BIOLOGICAL:** MF59 adjuvanted seasonal influenza vaccine

## Key facts

- **NCT ID:** NCT05035680
- **Lead sponsor:** Gates Medical Research Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2022-07-14
- **Primary completion:** 2023-03-25
- **Final completion:** 2023-11-25
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Study cancelled
- **Last updated:** 2022-11-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05035680

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05035680, "Proof of Concept Trial of Adjuvant Activity of SWE, a Squalene-based -Oil-in-water Emulsion". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05035680. Licensed CC0.

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