# Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.

> **NCT05036538** · NA · RECRUITING · sponsor: **Heart and Brain Research Group, Germany** · enrollment: 125 (estimated)

## Conditions studied

- Preoperative Stress
- Postoperative Cognitive Dysfunction
- Postoperative Delirium

## Interventions

- **DEVICE:** Intervention with natural sounds administered via headphones
- **DEVICE:** Intervention with natural sounds and binaural beats administered via headphones
- **DEVICE:** Intervention with natural sounds and virtual reality administered via headphones and head mounted display
- **DEVICE:** Intervention with natural sounds, binaural beats and virtual reality administered via headphones and head mounted display

## Key facts

- **NCT ID:** NCT05036538
- **Lead sponsor:** Heart and Brain Research Group, Germany
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-07-27
- **Primary completion:** 2028-08
- **Final completion:** 2028-11
- **Target enrollment:** 125 (ESTIMATED)
- **Last updated:** 2026-02-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05036538

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05036538, "Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT05036538. Licensed CC0.

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