# Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial

> **NCT05040464** · PHASE3 · RECRUITING · sponsor: **Centre Hospitalier Universitaire, Amiens** · enrollment: 166 (estimated)

## Conditions studied

- Crohn Disease
- Azathioprine
- Methotrexate

## Interventions

- **DRUG:** AZA capsules
- **DRUG:** MTX
- **BIOLOGICAL:** blood sample

## Key facts

- **NCT ID:** NCT05040464
- **Lead sponsor:** Centre Hospitalier Universitaire, Amiens
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-08-26
- **Primary completion:** 2026-08
- **Final completion:** 2027-05
- **Target enrollment:** 166 (ESTIMATED)
- **Last updated:** 2025-05-28

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05040464

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05040464, "Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT05040464. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*