# Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)

> **NCT05041907** · PHASE2 · RECRUITING · sponsor: **University of Oxford** · enrollment: 3800 (estimated)

## Conditions studied

- COVID-19

## Interventions

- **DRUG:** Nirmatrelvir/ritonavir (e.g. PAXLOVID™)
- **DRUG:** Nitazoxanide
- **DRUG:** Molnupiravir and nirmatrelvir/ritonavir (e.g. PAXLOVID™)
- **DRUG:** Hydroxychloroquine
- **OTHER:** No treatment
- **DRUG:** Monoclonal antibodies
- **DRUG:** Fluoxetine
- **DRUG:** Molnupiravir
- **DRUG:** Sotrovimab
- **DRUG:** Ensitrelvir
- **DRUG:** Monoclonal antibodies
- **DRUG:** Favipiravir
- **DRUG:** Ivermectin
- **DRUG:** Remdesivir
- **DRUG:** Atilotrelvir/ritonavir
- **DRUG:** Metformin
- **DRUG:** Nirmatrelvir/ritonavir
- **DRUG:** Nirmatrelvir/ritonavir
- **DRUG:** Nirmatrelvir

## Key facts

- **NCT ID:** NCT05041907
- **Lead sponsor:** University of Oxford
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-09-30
- **Primary completion:** 2027-01
- **Final completion:** 2027-01
- **Target enrollment:** 3800 (ESTIMATED)
- **Last updated:** 2026-02-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05041907

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05041907, "Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05041907. Licensed CC0.

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