# ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation

> **NCT05045261** · PHASE2 · UNKNOWN · sponsor: **ANRS, Emerging Infectious Diseases** · enrollment: 100 (estimated)

## Conditions studied

- Hepatitis B, Chronic

## Interventions

- **DRUG:** administration of SLGN in arm C
- **DRUG:** Discontinuation of NUC treatment in arms B and C

## Key facts

- **NCT ID:** NCT05045261
- **Lead sponsor:** ANRS, Emerging Infectious Diseases
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-02-01
- **Primary completion:** 2024-06-30
- **Final completion:** 2024-06-30
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2022-03-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05045261

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05045261, "ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05045261. Licensed CC0.

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