# Crosstalk Between Mucosal-Associated Invariant T (MAIT) Cells and the Gut Microbiota and Mucosa in the Development of Type 1 Diabetes in Children

> **NCT05054361** · — · RECRUITING · sponsor: **Institut National de la Santé Et de la Recherche Médicale, France** · enrollment: 180 (estimated)

## Conditions studied

- Type1diabetes

## Interventions

- **DIAGNOSTIC_TEST:** MAIT cells analysis
- **DIAGNOSTIC_TEST:** MAIT cytokines production analysis
- **DIAGNOSTIC_TEST:** Lactulose/Mannitol Test
- **PROCEDURE:** UGI Endoscopy
- **DIAGNOSTIC_TEST:** Coxsackie virus B infection status
- **DIAGNOSTIC_TEST:** Coxsackie virus B infection status

## Key facts

- **NCT ID:** NCT05054361
- **Lead sponsor:** Institut National de la Santé Et de la Recherche Médicale, France
- **Sponsor class:** OTHER_GOV
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2022-01-01
- **Primary completion:** 2026-08-11
- **Final completion:** 2027-08-14
- **Target enrollment:** 180 (ESTIMATED)
- **Last updated:** 2026-04-13

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05054361

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05054361, "Crosstalk Between Mucosal-Associated Invariant T (MAIT) Cells and the Gut Microbiota and Mucosa in the Development of Type 1 Diabetes in Children". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05054361. Licensed CC0.

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