# Aerosolized Endotracheal Lidocaine to Avoid Intracranial Pressure Spikes in Patients With Severe Traumatic Brain Injury

> **NCT05058677** · PHASE4 · COMPLETED · sponsor: **The University of Texas Health Science Center, Houston** · enrollment: 10 (actual)

## Conditions studied

- Traumatic Brain Injury

## Interventions

- **DRUG:** aerosolized 2% lidocaine (20mg/ml)
- **DRUG:** instilled 0.9% sodium chloride (NS)
- **DRUG:** instilled 2% lidocaine solution
- **PROCEDURE:** Endotracheal Suctioning (ETS)

## Key facts

- **NCT ID:** NCT05058677
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-11-09
- **Primary completion:** 2025-06-30
- **Final completion:** 2025-06-30
- **Target enrollment:** 10 (ACTUAL)
- **Last updated:** 2026-01-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05058677

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05058677, "Aerosolized Endotracheal Lidocaine to Avoid Intracranial Pressure Spikes in Patients With Severe Traumatic Brain Injury". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05058677. Licensed CC0.

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