# Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study

> **NCT05071352** · PHASE3 · COMPLETED · sponsor: **Cairo University** · enrollment: 60 (actual)

## Conditions studied

- Analgesia
- Critical Illness
- Mechanical Ventilation
- Sedation

## Interventions

- **DRUG:** Nefopam
- **DRUG:** Standard of care in the ICU for assessment and management of pain, sedation, and delirium.

## Key facts

- **NCT ID:** NCT05071352
- **Lead sponsor:** Cairo University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-10-01
- **Primary completion:** 2023-03-01
- **Final completion:** 2023-03-31
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2025-12-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05071352

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05071352, "Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT05071352. Licensed CC0.

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