# Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study

> **NCT05077735** · PHASE2 · RECRUITING · sponsor: **Mayo Clinic** · enrollment: 29 (estimated)

## Conditions studied

- Diffuse Midline Glioma, H3 K27M-Mutant

## Interventions

- **RADIATION:** Hypofractionated Radiation Therapy
- **OTHER:** Questionnaire Administration
- **PROCEDURE:** Magnetic Resonance Imaging
- **PROCEDURE:** Positron Emission Tomography and Computed Tomography Scan

## Key facts

- **NCT ID:** NCT05077735
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-10-11
- **Primary completion:** 2027-10-15
- **Final completion:** 2027-10-15
- **Target enrollment:** 29 (ESTIMATED)
- **Last updated:** 2026-01-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05077735

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05077735, "Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05077735. Licensed CC0.

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