# Evaluation of Emerging New Treatments for Infection Prevention in Total Joint Replacement

> **NCT05084378** · PHASE3 · COMPLETED · sponsor: **Hamilton Health Sciences Corporation** · enrollment: 495 (actual)

## Conditions studied

- Periprosthetic Joint Infection
- Draining Wound

## Interventions

- **DRUG:** Povidone-Iodine Lavage Solution
- **DRUG:** Chlorhexidine Lavage Solution
- **DRUG:** Topical Antibiotic
- **DRUG:** Saline Lavage Solution

## Key facts

- **NCT ID:** NCT05084378
- **Lead sponsor:** Hamilton Health Sciences Corporation
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-03-11
- **Primary completion:** 2024-08-04
- **Final completion:** 2024-10-28
- **Target enrollment:** 495 (ACTUAL)
- **Last updated:** 2025-06-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05084378

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05084378, "Evaluation of Emerging New Treatments for Infection Prevention in Total Joint Replacement". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05084378. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*