# Development of AWZ1066S, a Small Molecule Anti-Wolbachia Candidate Macrofilaricide Drug

> **NCT05084560** · PHASE1 · TERMINATED · sponsor: **Liverpool School of Tropical Medicine** · enrollment: 30 (actual)

## Conditions studied

- Filariasis, Lymphatic
- Onchocerciasis

## Interventions

- **DRUG:** AWZ1066S
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05084560
- **Lead sponsor:** Liverpool School of Tropical Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2021-12-10
- **Primary completion:** 2023-05-22
- **Final completion:** 2023-05-22
- **Target enrollment:** 30 (ACTUAL)
- **Why stopped:** Safety issues
- **Last updated:** 2023-09-21

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05084560

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05084560, "Development of AWZ1066S, a Small Molecule Anti-Wolbachia Candidate Macrofilaricide Drug". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05084560. Licensed CC0.

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