# Metabolic Adaptation to High-frequent Hypoglycaemia in Type 1 Diabetes

> **NCT05095259** · NA · UNKNOWN · sponsor: **Nordsjaellands Hospital** · enrollment: 60 (estimated)

## Conditions studied

- Type1diabetes

## Interventions

- **DRUG:** insulin human
- **DRUG:** Epinephrin
- **PROCEDURE:** Muscle biopsy
- **PROCEDURE:** Adipose tissue biopsy
- **DRUG:** Glucagon
- **DEVICE:** IPRO 2 Medtronic Minimed
- **PROCEDURE:** 7 Tesla (7T) Magnetic Resonance Imaging
- **PROCEDURE:** Indirect Calorimetry using Jaeger Oxycon Champion
- **PROCEDURE:** Core temperature and thermography using Thermovision SC645
- **DEVICE:** Freestyle Libre 2

## Key facts

- **NCT ID:** NCT05095259
- **Lead sponsor:** Nordsjaellands Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-12-16
- **Primary completion:** 2023-12
- **Final completion:** 2023-12
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2023-05-03

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05095259

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05095259, "Metabolic Adaptation to High-frequent Hypoglycaemia in Type 1 Diabetes". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05095259. Licensed CC0.

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