# A Study to Determine the Abuse Potential of Seltorexant Compared to Suvorexant and Zolpidem

> **NCT05106153** · PHASE1 · COMPLETED · sponsor: **Janssen Research & Development, LLC** · enrollment: 127 (actual)

## Conditions studied

- Healthy Non-dependent, Recreational Sedative Users
- Abuse Potential

## Interventions

- **DRUG:** Suvorexant
- **DRUG:** Zolpidem
- **DRUG:** Seltorexant
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05106153
- **Lead sponsor:** Janssen Research & Development, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-12-17
- **Primary completion:** 2023-05-12
- **Final completion:** 2023-05-12
- **Target enrollment:** 127 (ACTUAL)
- **Last updated:** 2025-04-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05106153

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05106153, "A Study to Determine the Abuse Potential of Seltorexant Compared to Suvorexant and Zolpidem". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05106153. Licensed CC0.

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