# A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma

> **NCT05119010** · NA · TERMINATED · sponsor: **Gustave Roussy, Cancer Campus, Grand Paris** · enrollment: 3 (actual)

## Conditions studied

- Metastatic Renal Cell Carcinoma

## Interventions

- **DIETARY_SUPPLEMENT:** Continuous ketogenic diet
- **DIETARY_SUPPLEMENT:** Discontinuous ketogenic diet
- **DIETARY_SUPPLEMENT:** beta-hydroxybutyrate (BHB) supplementation

## Key facts

- **NCT ID:** NCT05119010
- **Lead sponsor:** Gustave Roussy, Cancer Campus, Grand Paris
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2023-03-24
- **Primary completion:** 2024-05-22
- **Final completion:** 2024-05-22
- **Target enrollment:** 3 (ACTUAL)
- **Why stopped:** Recruitment challenges: competition with another microbiome trial, patient refusal to join a dietary intervention study, poor tolerance of oral DPD (Grade 2 mucositis), and issues with organizing biological sample collection.
- **Last updated:** 2024-12-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05119010

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05119010, "A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT05119010. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*