# Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy

> **NCT05129748** · PHASE2 · RECRUITING · sponsor: **Sunnybrook Health Sciences Centre** · enrollment: 92 (estimated)

## Conditions studied

- Ototoxic Hearing Loss

## Interventions

- **DRUG:** Sodium Thiosulfate + Mannitol

## Key facts

- **NCT ID:** NCT05129748
- **Lead sponsor:** Sunnybrook Health Sciences Centre
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-02-15
- **Primary completion:** 2027-01
- **Final completion:** 2027-12
- **Target enrollment:** 92 (ESTIMATED)
- **Last updated:** 2023-04-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05129748

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05129748, "Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05129748. Licensed CC0.

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