# Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

> **NCT05139056** · PHASE1 · SUSPENDED · sponsor: **City of Hope Medical Center** · enrollment: 36 (estimated)

## Conditions studied

- Currently Only Enrolling Glioblastoma Patients at First Recurrence

## Interventions

- **BIOLOGICAL:** Neural Stem Cells-expressing CRAd-S-pk7
- **PROCEDURE:** Resection

## Key facts

- **NCT ID:** NCT05139056
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** SUSPENDED
- **Start date:** 2023-05-02
- **Primary completion:** 2026-08-07
- **Final completion:** 2026-08-07
- **Target enrollment:** 36 (ESTIMATED)
- **Why stopped:** Safety issues
- **Last updated:** 2026-03-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05139056

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05139056, "Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas". Retrieved via AI Analytics 2026-06-10 from https://api.ai-analytics.org/clinical/NCT05139056. Licensed CC0.

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