# Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer

> **NCT05144542** · NA · ACTIVE_NOT_RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 140 (estimated)

## Conditions studied

- Lung Carcinoma

## Interventions

- **PROCEDURE:** Participants will vape electronic cigarettes for 26 weeks.
- **DRUG:** Nicotine Replacement
- **DRUG:** Nicotine Replacement

## Key facts

- **NCT ID:** NCT05144542
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-03-07
- **Primary completion:** 2026-10-17
- **Final completion:** 2026-10-17
- **Target enrollment:** 140 (ESTIMATED)
- **Last updated:** 2026-04-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05144542

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05144542, "Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT05144542. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
