# A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia

> **NCT05146778** · NA · RECRUITING · sponsor: **Gangnam Severance Hospital** · enrollment: 230 (estimated)

## Conditions studied

- Breast Cancer
- Mastectomy
- Pain, Chronic
- Pain, Post Operative

## Interventions

- **PROCEDURE:** Opioid-free anesthesia
- **PROCEDURE:** Conventional opioid-based anesthesia

## Key facts

- **NCT ID:** NCT05146778
- **Lead sponsor:** Gangnam Severance Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-12-16
- **Primary completion:** 2026-07-31
- **Final completion:** 2027-10-31
- **Target enrollment:** 230 (ESTIMATED)
- **Last updated:** 2025-11-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05146778

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05146778, "A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05146778. Licensed CC0.

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