# RNS System NAUTILUS Study

> **NCT05147571** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **NeuroPace** · enrollment: 100 (actual)

## Conditions studied

- Epilepsy
- Idiopathic Generalized Epilepsy
- Generalized Tonic Clonic Seizure

## Interventions

- **DEVICE:** Responsive stimulation
- **DEVICE:** Sham stimulation

## Key facts

- **NCT ID:** NCT05147571
- **Lead sponsor:** NeuroPace
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-08-09
- **Primary completion:** 2025-04-04
- **Final completion:** 2026-03
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2025-07-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05147571

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05147571, "RNS System NAUTILUS Study". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05147571. Licensed CC0.

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