# Folic Acid and Intensive Antihypertensive Therapy for Hypertension With CSVD

> **NCT05169021** · PHASE4 · NOT_YET_RECRUITING · sponsor: **Beijing Tiantan Hospital** · enrollment: 15000 (estimated)

## Conditions studied

- Cerebral Small Vessel Diseases
- Stroke

## Interventions

- **DRUG:** Amlodipine folic acid 5.8mg+intensive antihypertensive therapy
- **DRUG:** Amlodipine folic acid 5.8mg+standard antihypertensive therapy
- **DRUG:** Amlodipine+intensive antihypertensive therapy
- **DRUG:** Amlodipine+standard antihypertensive therapy

## Key facts

- **NCT ID:** NCT05169021
- **Lead sponsor:** Beijing Tiantan Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2021-12-31
- **Primary completion:** 2024-12-31
- **Final completion:** 2028-12-31
- **Target enrollment:** 15000 (ESTIMATED)
- **Last updated:** 2021-12-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05169021

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05169021, "Folic Acid and Intensive Antihypertensive Therapy for Hypertension With CSVD". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT05169021. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*