# Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)

> **NCT05172271** · NA · ACTIVE_NOT_RECRUITING · sponsor: **National Institute of Mental Health (NIMH)** · enrollment: 8 (actual)

## Conditions studied

- Major Depressive Disorder
- Bipolar Disorder
- Unipolar Major Depression

## Interventions

- **DEVICE:** MagPro TMS Stimulator and coil
- **DEVICE:** Thymatron(R) System IV
- **DEVICE:** Magnetic Resonance Imaging Scanner
- **OTHER:** ECT device without stimulation

## Key facts

- **NCT ID:** NCT05172271
- **Lead sponsor:** National Institute of Mental Health (NIMH)
- **Sponsor class:** NIH
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-11-08
- **Primary completion:** 2027-07-31
- **Final completion:** 2027-10-31
- **Target enrollment:** 8 (ACTUAL)
- **Last updated:** 2026-03-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05172271

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05172271, "Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05172271. Licensed CC0.

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