Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast Cancer
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Conditions
- Anatomic Stage III Breast Cancer AJCC v8
- Anatomic Stage IIIA Breast Cancer AJCC v8
- Anatomic Stage IIIB Breast Cancer AJCC v8
- Anatomic Stage IIIC Breast Cancer AJCC v8
- Anatomic Stage IV Breast Cancer AJCC v8
- Breast Inflammatory Carcinoma
- Invasive Breast Carcinoma
- Prognostic Stage III Breast Cancer AJCC v8
- Prognostic Stage IIIA Breast Cancer AJCC v8
- Prognostic Stage IIIB Breast Cancer AJCC v8
- Prognostic Stage IIIC Breast Cancer AJCC v8
- Prognostic Stage IV Breast Cancer AJCC v8
- Triple-Negative Breast Carcinoma
Interventions
- DRUG: Carboplatin
- DRUG: Cyclophosphamide
- DRUG: Doxorubicin
- DRUG: Paclitaxel
- BIOLOGICAL: Panitumumab
- BIOLOGICAL: Pembrolizumab
Sponsor
M.D. Anderson Cancer Center
Collaborators